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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFKB2
All Species:
18.79
Human Site:
Y446
Identified Species:
45.93
UniProt:
Q00653
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00653
NP_001070961.1
900
96749
Y446
M
L
Q
R
A
R
E
Y
N
A
R
L
F
G
L
Chimpanzee
Pan troglodytes
XP_001168576
837
90846
L427
I
I
H
L
H
S
Q
L
V
R
D
L
L
E
V
Rhesus Macaque
Macaca mulatta
XP_001104566
876
94023
Y446
M
L
Q
R
A
R
E
Y
N
A
R
L
F
C
L
Dog
Lupus familis
XP_850995
899
96492
Y446
L
L
Q
R
A
R
E
Y
N
A
R
L
F
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTK5
899
96814
Y446
T
L
Q
R
A
R
E
Y
N
A
R
L
F
G
L
Rat
Rattus norvegicus
NP_001008350
898
96721
Y445
T
L
Q
R
A
R
E
Y
N
A
R
L
F
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98150
906
99648
N442
L
W
L
L
A
R
R
N
A
H
A
L
L
D
Y
Frog
Xenopus laevis
O73630
958
105836
A459
C
Q
M
I
M
R
Q
A
N
L
R
M
L
S
L
Zebra Danio
Brachydanio rerio
NP_001001840
902
98760
C457
R
A
N
L
A
A
K
C
N
A
R
A
L
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999819
1125
124026
S614
T
D
D
I
T
I
D
S
D
S
M
A
W
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.1
95.1
92.5
N.A.
91.7
90.8
N.A.
N.A.
66.8
50.9
49.6
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
55
96
95.1
N.A.
94.8
94.1
N.A.
N.A.
76.7
65.9
65.1
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
26.6
40
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
70
10
0
10
10
60
10
20
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% C
% Asp:
0
10
10
0
0
0
10
0
10
0
10
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
50
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
0
% G
% His:
0
0
10
0
10
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
10
10
0
20
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
20
50
10
30
0
0
0
10
0
10
0
70
40
10
60
% L
% Met:
20
0
10
0
10
0
0
0
0
0
10
10
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
70
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
50
0
0
0
20
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
0
50
0
70
10
0
0
10
70
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
10
0
10
0
0
0
10
0
% S
% Thr:
30
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
20
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _